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Researchers at Weill Cornell Medicine have uncovered how a key Parkinson's protein called LRRK2 shifts between inactive and active forms, revealing the structural changes that enable certain mutations to push the protein into an overactive state. Mutations that cause LRRK2 to bec

Researchers have identified genetic changes in malaria parasites that may reduce the effectiveness of key antimalarial medicines, highlighting the need for continued surveillance.

A favorite toy or treat can become dangerous in an instant if it gets lodged in your pet's airway. Because choking is a terrifying emergency for pets and their owners, Dr. Christine Rutter, a clinical associate professor at the Texas A&M College of Veterinary Medicine and Biomedi

A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine approaches to treat organ rejection.

If you are in severe pain and struggling to get opioid medication in Indonesia, you are not alone. Despite the International Narcotics Control Board (INCB) recognizing several therapeutic opioids as essential medicines, Indonesia has one of the lowest levels of medical opioid use

A long-running debate over prescription drug costs has centered on whether drug manufacturers are better rewarded for truly innovative medicines or so-called "me-too" drugs that may offer only incremental improvements over existing treatments but still command high prices.

Northwestern Medicine scientists have uncovered how a major Parkinson's disease gene disrupts the brain's most vulnerable dopamine-producing neurons before detectable neuronal loss. The study offers new clues for developing treatments that target the disease in its earliest stage

When it comes to maintaining healthy bones, how intensely we exercise may matter more than how much we exercise, according to researchers at Semmelweis University. Their study, published in Sports Medicine – Open, found that bone formation was stimulated most effectively by activ

Hepatitis C remains a major cause of liver cirrhosis and liver cancer worldwide. Although highly effective antiviral medicines can cure most infections, many people remain undiagnosed or untreated because health care systems often fail to reach those at greatest risk.

Scientists have figured out how two famously poisonous plants create chemicals with surprising medical potential. After tracking thousands of genes in wolfsbane and larkspur, they identified six enzymes needed to build a complex compound called atisinium. The team recreated the p

A traditional Japanese medicine used for obesity may do more than support weight loss. Researchers at the University of Osaka, working with Kobayashi Pharmaceutical Co., Ltd., investigated whether Bofutsushosan could protect aging tissues from fibrosis—the excessive buildup of sc

One in eight mothers in England is now diagnosed with gestational diabetes, with diagnoses rising by 60% in just five years, according to a major study published in the journal BMJ Medicine.